Abstract The vast majority of adult cancer cells achieve cellular immortality by activating a telomere maintenance mechanism (TMM). While this is mostly achieved by the de-silencing of hTERT telomerase gene expression. an alternative homologous recombination-based and telomerase-independent mechanism. known as ALT (Alternative Lengthening of Telomeres). https://thecookiecountesses.shop/product-category/pyo-supplies/