Abstract Clearance of protein waste products from the brain is accomplished by a combination of advection and diffusion in cerebrospinal fluid (CSF) and interstitial fluid (ISF). In the glymphatic model. there is a flow of ISF in the interstitial space. and both advection and diffusion occur there. https://www.bekindtopets.com/mega-offer-14-x2-125-Knobby-Tire-for-the-Gyroor-C3-Electric-Bike-quick-super/