Abstract Head and neck squamous cell carcinoma (HNSCC) is a highly malignant disease with high death rates that have remained substantially unaltered for decades. Therefore. new treatment approaches are urgently needed. Human papillomavirus-negative tumors harbor areas of terminally differentiated tissue that are characterized by cornification. https://www.roneverhart.com/DPA-d-fine-Slim-Capsule-Headset-Mic-Single-Ear-40mm-Boom-Interchangeable-Black-p7600/