Cell spheroids are a widely used model to investigate cell-cell and cell-matrix interactions in a 3D microenvironment in vitro. Most research on cell spheroids has been focused on their response to various stimuli under static conditions. Recently. the effect of flow on cell spheroids has been investigated in the context of tumor invasion in interstitial space. https://www.diariolahumanidad.com/product-category/sheffield-silverplate/